KMID : 0603820100160030169
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Journal of Experimental & Biomedical Science 2010 Volume.16 No. 3 p.169 ~ p.177
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Relationship among Bone Mineral Density, Body Composition, and Metabolic Syndrome Risk Factors in Females
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Kim Tai-Jeon
Cha Byung-Heun Shin Kyung-A
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Abstract
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Osteoporosis is a disease that increases the fracture rates and a major cause of increased mortality and morbidity in the elderly people. This study is to determine which components of body composition and metabolic syndrome risk factors are important to bone health, we analysed the relationship among bone mineral density (BMD), body composition and metabolic syndrome risk factors in females. Totally 630 females participated in a medical check-up program (mean age 47 years) were selected for this study. Body composition analysis was performed by segmental bioelectrical impedance method, muscle mass, and percent body fat were measured. We also measured metabolic syndrome risk factors including abdominal obesity, HDL-cholesterol, triglyceride, blood pressure and fasting glucose level. Metabolic syndrome was defined by NCEP-ATP ¥² criteria. The lumbar spine and femoral neck BMD were measured using the dual energy X-ray absorptiometry. Osteopenia and osteoporosis were observed in 180 and 51 persons, respectively. Muscle mass and HDL-cholesterol decreased in osteopenia and osteoporosis groups compared to the control group, and the grade was shown progressively by the symptoms. Significant positive correlation between BMD and muscle mass was observed. Multi variable regression analyses showed that % body fat and muscle mass were independent predictors of BMD after adjustment of age, height and weight. In conclusion, the BMD showed negative correlation with the metabolic syndrome, and body composition was associated with BMD.
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KEYWORD
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Bone mineral density, Metabolic syndrome, Body composition, Osteoporosis, Osteopenia
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